Methotex 1Gm/40Ml – 25Mg/Ml Injection contains ‘Methotrexate’ that works by interrupting the processes of the immune system that cause inflammation in the joint tissues. It reduces pain and inflammation and delays joint damage and disease progression over time. Besides this, Methotex 1Gm/40Ml – 25Mg/Ml Injection prevents and stops the growth of cancer cells, thereby helps treat cancer. Methotex 1Gm/40Ml – 25Mg/Ml Injection treats psoriasis by suppressing the overactive immune system that is responsible for causing psoriasis.
In some cases, Methotex 1Gm/40Ml – 25Mg/Ml Injection may cause common side-effects such as nausea, vomiting, diarrhoea, unusual fatigue, dizziness, headache, loss of appetite, lowered resistance to infections, tingling sensation, leukopenia (decreased number of white blood cells), and soreness of mouth and lips. You are advised to talk to your doctor if you experience these side effects persistently.
Take Methotex 1Gm/40Ml – 25Mg/Ml Injection exactly as prescribed by the doctor; daily intake of Methotex 1Gm/40Ml – 25Mg/Ml Injection could lead to serious toxic effects. Do not take Methotex 1Gm/40Ml – 25Mg/Ml Injection if you are pregnant or breastfeeding. Methotex 1Gm/40Ml – 25Mg/Ml Injection may cause dizziness and fatigue, so drive only if you are alert. Avoid consuming alcohol whilst on treatment with Methotex 1Gm/40Ml – 25Mg/Ml Injection. Your doctor may advise you to undergo regular blood tests, kidney and liver tests to monitor your condition. Inform your doctor about your medications and health condition to rule out any unpleasant side effects/interactions.
Uses of Methotex 1Gm/40Ml – 25Mg/Ml Injection
Rheumatoid arthritis, Psoriatic arthritis, Psoriasis, Cancer
Medicinal Benefits
Methotex 1Gm/40Ml – 25Mg/Ml Injection belongs to the class of medicines called ‘anti-metabolites and immunosuppressants’ used to treat active rheumatoid arthritis, including polyarticular juvenile rheumatoid arthritis (arthritis in children), severe psoriasis, and severe psoriatic arthritis. Methotex 1Gm/40Ml – 25Mg/Ml Injection helps treat rheumatoid arthritis and psoriatic arthritis by interrupting the processes of the immune system that cause inflammation in the joint tissues. It reduces pain and inflammation and delays joint damage and disease progression over time. Methotex 1Gm/40Ml – 25Mg/Ml Injection treats psoriasis by suppressing the overactive immune system that is responsible for causing psoriasis. Methotex 1Gm/40Ml – 25Mg/Ml Injection is used alone or in combination with other medicines to treat breast cancer, lung cancer, head and neck cancer, mycosis fungoides (type of blood cancer), and advanced stage non-Hodgkin’s lymphomas (cancer that starts in the lymphatic system). Methotex 1Gm/40Ml – 25Mg/Ml Injection prevents and stops the growth of cancer cells by interfering with DNA production. Methotex 1Gm/40Ml – 25Mg/Ml Injection may also be used to treat inflammatory bowel disease.
Directions for Use
Storage
Side Effects of Methotex 1Gm/40Ml – 25Mg/Ml Injection
- Nausea
- Vomiting
- Diarrhoea
- Unusual fatigue
- Dizziness
- Headache
- Loss of appetite
- Elevated liver enzymes
- Lowered resistance to infections
- Tingling sensation
- Leukopenia (decreased number of white blood cells)
- Soreness of mouth and lips
In-Depth Precautions and Warning
Drug Warnings
Do not take Methotex 1Gm/40Ml – 25Mg/Ml Injection if you are allergic to any of its contents; if you have immunodeficiency conditions, bone marrow problems, low white blood cell count, low platelet count, serious anaemia, liver problems due to alcohol abuse, chronic liver disease; if you are pregnant or breastfeeding. Talk to your doctor before taking Methotex 1Gm/40Ml – 25Mg/Ml Injection if you have/had liver or kidney problems, ulceration in the stomach or bowels, poor general condition, received any vaccinations or if you are due to have any vaccinations, diabetes, ascites (fluid in the stomach area), lung problems or fluid in the lungs. Methotex 1Gm/40Ml – 25Mg/Ml Injection may cause dizziness and fatigue, so drive only if you are alert. Take Methotex 1Gm/40Ml – 25Mg/Ml Injection exactly as directed by the doctor as it may cause serious problems if not taken in the dose and duration prescribed by the doctor. Stop taking Methotex 1Gm/40Ml – 25Mg/Ml Injection and consult your doctor immediately if you have mouth sores, diarrhoea, a fever, dehydration, cough, bleeding, shortness of breath, any signs of infection, or a skin rash.
Drug Interactions
Drug-Drug Interactions: Methotex 1Gm/40Ml – 25Mg/Ml Injection may interact with pain killers (celecoxib, acetaminophen, hydrocodone), anti-depressant (duloxetine), immunosuppressants (etanercept), anti-rheumatoid (adalimumab), antacid (esomeprazole), and anti-malarial (hydroxychloroquine).
Drug-Food Interactions: Avoid consuming alcohol whilst on treatment with Methotex 1Gm/40Ml – 25Mg/Ml Injection.
Drug-Disease Interactions: Inform your doctor if you have immunodeficiency conditions, bone marrow problems, low white blood cell count, low platelet count, serious anaemia, liver problems due to alcohol abuse, or chronic liver disease.
Safety Advice
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ALCOHOL
CONSULT YOUR DOCTOR
You are recommended to avoid alcohol consumption while taking Methotex 1Gm/40Ml – 25Mg/Ml Injection.
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PREGNANCY
CONSULT YOUR DOCTOR
Methotex 1Gm/40Ml – 25Mg/Ml Injection may cause serious birth defects. It is not recommended to take Methotex 1Gm/40Ml – 25Mg/Ml Injection while you are pregnant.
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BREAST FEEDING
CONSULT YOUR DOCTOR
Methotex 1Gm/40Ml – 25Mg/Ml Injection passes into breast milk. Avoid breastfeeding whilst on treatment with Methotex 1Gm/40Ml – 25Mg/Ml Injection.
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DRIVING
Methotex 1Gm/40Ml – 25Mg/Ml Injection may cause dizziness and tiredness; do not drive or operate heavy machinery if you experience these symptoms.
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LIVER
Do not take Methotex 1Gm/40Ml – 25Mg/Ml Injection if you have chronic liver disease. Please consult your doctor if you have liver impairment before taking Methotex 1Gm/40Ml – 25Mg/Ml Injection.
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KIDNEY
Please consult your doctor if you have kidney impairment before taking Methotex 1Gm/40Ml – 25Mg/Ml Injection.
