Monoclonal antibodies are derived from hybridoma cell lines, created by fusing mouse antibody producing B lymphocytes with mouse myeloma cells or are derived from a human B cell line through EBV transformation. Each hybridoma cell line produces homogenous antibodies of only one immunoglobulin class, which are identical in their chemical structure and immunological activity. Human red blood cells are classified as Rho (D) positive and Rho (D) negative depending upon the presence or absence of D (Rho) antigen on them. Approximately 85% of the Caucasian population are Rho (D) positive.
REAGENT MaxCLONE Anti-D (IgM) is a ready-to-use reagent prepared from supernatants of cell cultures with antibody-producing B lymphocytes obtained through EBV transformation. These antibodies are monoclonal antibodies of the same specificity having the capability of recognizing specific epitopes of the human red blood cell antigen D. Each batch of reagent undergoes rigorous quality control at various stages of manufacture for its specificity, avidity and performance.
REAGENT STORAGE AND STABILITY
1. Store the reagent at 2-8 C. DO NOT FREEZE.
2. The shelf life of the reagent is as per the expiry date mentioned on the reagent vial label. Once opened, the shelf life of the reagent vial is as described on the reagent vial label, provided it is not contaminated.
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